diff --git a/src/core/memory.cpp b/src/core/memory.cpp
index 8a83de904..d8aab7090 100644
--- a/src/core/memory.cpp
+++ b/src/core/memory.cpp
@@ -296,7 +296,7 @@ u8* GetPhysicalPointer(PAddr address) {
     return target_pointer;
 }
 
-void RasterizerFlushVirtualRegion(VAddr start, u32 size, FlushMode mode) {
+void RasterizerFlushVirtualRegion(VAddr start, u64 size, FlushMode mode) {
     // Since pages are unmapped on shutdown after video core is shutdown, the renderer may be
     // null here
     if (VideoCore::g_renderer == nullptr) {
@@ -313,7 +313,7 @@ void RasterizerFlushVirtualRegion(VAddr start, u32 size, FlushMode mode) {
 
         VAddr overlap_start = std::max(start, region_start);
         VAddr overlap_end = std::min(end, region_end);
-        u32 overlap_size = overlap_end - overlap_start;
+        u64 overlap_size = overlap_end - overlap_start;
 
         auto* rasterizer = VideoCore::g_renderer->Rasterizer();
         switch (mode) {
diff --git a/src/core/memory.h b/src/core/memory.h
index 1c7232115..3e2c3f23d 100644
--- a/src/core/memory.h
+++ b/src/core/memory.h
@@ -269,6 +269,6 @@ enum class FlushMode {
  * Flushes and invalidates any externally cached rasterizer resources touching the given virtual
  * address region.
  */
-void RasterizerFlushVirtualRegion(VAddr start, u32 size, FlushMode mode);
+void RasterizerFlushVirtualRegion(VAddr start, u64 size, FlushMode mode);
 
 } // namespace Memory
diff --git a/src/video_core/rasterizer_interface.h b/src/video_core/rasterizer_interface.h
index 6514d7ded..a493e1d60 100644
--- a/src/video_core/rasterizer_interface.h
+++ b/src/video_core/rasterizer_interface.h
@@ -25,14 +25,14 @@ public:
     virtual void FlushAll() = 0;
 
     /// Notify rasterizer that any caches of the specified region should be flushed to 3DS memory
-    virtual void FlushRegion(VAddr addr, u32 size) = 0;
+    virtual void FlushRegion(VAddr addr, u64 size) = 0;
 
     /// Notify rasterizer that any caches of the specified region should be invalidated
-    virtual void InvalidateRegion(VAddr addr, u32 size) = 0;
+    virtual void InvalidateRegion(VAddr addr, u64 size) = 0;
 
     /// Notify rasterizer that any caches of the specified region should be flushed to 3DS memory
     /// and invalidated
-    virtual void FlushAndInvalidateRegion(VAddr addr, u32 size) = 0;
+    virtual void FlushAndInvalidateRegion(VAddr addr, u64 size) = 0;
 
     /// Attempt to use a faster method to perform a display transfer with is_texture_copy = 0
     virtual bool AccelerateDisplayTransfer(const void* config) {
diff --git a/src/video_core/renderer_opengl/gl_rasterizer.cpp b/src/video_core/renderer_opengl/gl_rasterizer.cpp
index b51614c25..09828e48d 100644
--- a/src/video_core/renderer_opengl/gl_rasterizer.cpp
+++ b/src/video_core/renderer_opengl/gl_rasterizer.cpp
@@ -194,17 +194,17 @@ void RasterizerOpenGL::FlushAll() {
     res_cache.FlushAll();
 }
 
-void RasterizerOpenGL::FlushRegion(VAddr addr, u32 size) {
+void RasterizerOpenGL::FlushRegion(VAddr addr, u64 size) {
     MICROPROFILE_SCOPE(OpenGL_CacheManagement);
     res_cache.FlushRegion(addr, size);
 }
 
-void RasterizerOpenGL::InvalidateRegion(VAddr addr, u32 size) {
+void RasterizerOpenGL::InvalidateRegion(VAddr addr, u64 size) {
     MICROPROFILE_SCOPE(OpenGL_CacheManagement);
     res_cache.InvalidateRegion(addr, size, nullptr);
 }
 
-void RasterizerOpenGL::FlushAndInvalidateRegion(VAddr addr, u32 size) {
+void RasterizerOpenGL::FlushAndInvalidateRegion(VAddr addr, u64 size) {
     MICROPROFILE_SCOPE(OpenGL_CacheManagement);
     res_cache.FlushRegion(addr, size);
     res_cache.InvalidateRegion(addr, size, nullptr);
diff --git a/src/video_core/renderer_opengl/gl_rasterizer.h b/src/video_core/renderer_opengl/gl_rasterizer.h
index f5c7b1162..b387f383b 100644
--- a/src/video_core/renderer_opengl/gl_rasterizer.h
+++ b/src/video_core/renderer_opengl/gl_rasterizer.h
@@ -32,9 +32,9 @@ public:
     void DrawTriangles() override;
     void NotifyMaxwellRegisterChanged(u32 id) override;
     void FlushAll() override;
-    void FlushRegion(VAddr addr, u32 size) override;
-    void InvalidateRegion(VAddr addr, u32 size) override;
-    void FlushAndInvalidateRegion(VAddr addr, u32 size) override;
+    void FlushRegion(VAddr addr, u64 size) override;
+    void InvalidateRegion(VAddr addr, u64 size) override;
+    void FlushAndInvalidateRegion(VAddr addr, u64 size) override;
     bool AccelerateDisplayTransfer(const void* config) override;
     bool AccelerateTextureCopy(const void* config) override;
     bool AccelerateFill(const void* config) override;